Dr Maike Bublitz

Maike Bublitz
Associate Professor of Microbial Biophysics and Ron Bancroft Fellow in Biochemistry
Dr
Maike
Bublitz

I studied Biology at the Technical University of Braunschweig in Germany, and subsequently obtained my PhD in Natural Sciences (Dr. rer. nat.) at the Helmholtz Centre for Infection Research.

After that, I spent several years as a Postdoctoral Fellow and Senior Advisor at Aarhus University in Denmark. During that time, I also worked part-time as a scientist in the drug discovery company PCovery in Copenhagen.

In early 2015, I accepted a Junior Research Group Leader position at the Institute of Biochemistry of the Goethe-University Frankfurt, and in November 2015, I joined the University of Oxford as an Associate Professor in Microbial Biophysics and a Tutorial Fellow of Oriel College.

Associated courses
Research interests

My research interests include X-ray crystallography, membrane protein structure and function, and drug development against pathogenic bacteria and fungi.

Selected publications

2016

Hahn A, Parey K, Bublitz M, Mills DJ, Zickermann V, Vonck J, Kühlbrandt W, Meier T. (2016) Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology. Mol Cell 63(3):445-56.

Clausen* JD, Bublitz* M, Arnou B, Olesen C, Andersen JP, Møller JV, Nissen P (2016) Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase. Structure. 24(4):617-23.

Bublitz M (Editor) (2016) P-Type ATPases - Methods and Protocols. Humana Press Inc. ISBN: 978-1-4939-3179-8.

Karlsen JL, Bublitz M. (2016) How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations: The P-Type ATPase Example. Methods Mol Biol. 1377:523-39.

2015

Nass K, Foucar L, Barends TR, Hartmann E, Botha S, Shoeman RL, Doak RB, Alonso-Mori R, Aquila A, Bajt S, Barty A, Bean R, Beyerlein KR, Bublitz M, Drachmann N, Gregersen J, Jönsson HO, Kabsch W, Kassemeyer S, Koglin JE, Krumrey M, Mattle D, Messerschmidt M, Nissen P, Reinhard L, Sitsel O, Sokaras D, Williams GJ, Hau-Riege S, Timneanu N, Caleman C, Chapman HN, Boutet S, Schlichting I. (2015) Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. J Synchrotron Radiat. 22(Pt 2):225-38. 

Bublitz M, Nass K, Drachmann ND, Markvardsen AJ, Gutmann MJ, Barends TR, Mattle D, Showman RL, Doak RB, Boutet S, Messerschmidt M, Seiert MM, Williams GJ, Foucar L, Reinhard L, Sitsel O, Gregersen JL, Clausen JD, Boesen T, Gotfryd K, Wang KT, Olesen C, Møller JV, Nissen P, Schlichting I. (2015) Structural studies of P-type ATPase ligand complexes using an X-ray free-electron laser, IUCrJ 2(4):409-20. 

2014

Penner RC, Andersen ES, Jensen JL, Kantcheva AK, Bublitz M, Nissen P, Rasmussen AMH, Svane KL, Hammer B, Rezazadegan R, Nielsen NC, Nielsen JT, Andersen JE (2014). Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. Nat Commun 5:5803. doi: 10.1038/ncomms6803.

Montigny C, Decottignies P, le Maréchal P, Capy P, Bublitz M, Olesen C, Møller JV, Nissen P, le Maire M (2014). S-Palmitoylation and S-Oleoylation of Rabbit and Pig Sarcolipin. J Biol Chem  289(49):33850-61.

Drachmann ND, Olesen C, Møller JV, Guo Z, Nissen P, Bublitz M (2014). Comparing crystal structures of Ca2+-ATPase in the presence of different lipidsFEBS J281(18):4249-62. 

2013

Clausen* JD, Bublitz* M, Arnou B, Montigny C, Jaxel C, Møller JV, Nissen P, Andersen JP, le Maire M (2013). SERCA mutant E309Q binds two Ca2+ ions but adopts a catalytically incompetent conformation. EMBO J, 32(24):3231-43. 

Winther* AM, Bublitz* M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ (2013). The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature, 495(7440):265-69. 

Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt, B, Morth JP, Møller JV, Nissen P (2013). Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.J Biol Chem, 288:10759-65. 

More publications...